Cerebral Endothelial Damage after Severe Head Injury

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Cerebral endothelial damage after severe head injury.

We demonstrate that in head injuries the degree of cerebral endothelial activation or injury depends on the type of brain injury and the patients age, and that in severe head injuries measuring the serum levels of thrombomodulin (TM) and von Willebrand factor (vWF) is useful in evaluating cerebral endothelial injury and activation. The values of vWF in the cases of focal brain injury were signi...

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Secondary ischaemic brain damage after head injury.

When the brain is examined within a few days of injury it can be surprisingly difficult to establish what has been the cause of death, or to determine with certainty which lesions are primary and which are secondary, apart from clear-cut complications such as intracranial haematoma or infection. Recent reports of continuous measurements of intracranial pressure after head injury (Lundberg, Trou...

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Cognitive recovery after severe head injury

SYNOPSIS The Wechsler Adult Intelligence Scale (WAIS) was administered to two matched groups of severely head-injured patients. The first administration was early in the recovery period, when group I was still in post-traumatic amnesia. The WAIS results for this group were significantly lower than those of group II, who were fully conscious. A follow-up at a later stage of recovery found that g...

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When seen after head trauma, subarachnoid hemorrhage (SAH) often leads to an angiogram to look for vascular injury. Usually the study is negative; sometimes a traumatic aneurysm or dissection is seen. Occasionally, a conventional saccular aneurysm is found. The clinical history, physical examination, and computed tomography (CT) scan in such a patient may suggest that an aneurysmal SAH was the ...

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ژورنال

عنوان ژورنال: Journal of Nippon Medical School

سال: 2007

ISSN: 1345-4676,1347-3409

DOI: 10.1272/jnms.74.332